Ambrisentan is a topic covered in the Consumer DrugInfo.

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General

Pronunciation:
(am'' bri sen' tan)

Brand name:

  • Letairis®

Important Warning

Do not take ambrisentan if you are pregnant or plan to become pregnant. Ambrisentan may harm the fetus. If you are a woman and able to become pregnant, you should not begin taking ambrisentan until a pregnancy test has shown that you are not pregnant. You must use two reliable methods of birth control during treatment with this medication and for 1 month after stopping treatment. Do not have unprotected sex. Talk to your doctor about birth control methods that will work for you. Call your doctor immediately if you miss a menstrual period or think you may be pregnant while you are taking ambrisentan.

Because of the risk of birth defects, ambrisentan is available to females only through a special restricted distribution program. A program called Letairis REMS ( Risk Evaluation and Mitigation Strategy) has been set up to make sure that female patient have appropriate lab tests before and while they are receiving ambrisentan. Women can get ambrisentan only if they are registered with this program. Your doctor must enroll you in this program. You can only receive the medication from a doctor and pharmacy that participates in the program. Ask your doctor if you have any questions about participating in the program or how to get your medication.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests during your treatment with ambrisentan.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with ambrisentan and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

Talk to your doctor about the risks of taking ambrisentan.

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